Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.380 | Biomarker | group | CTD_human | We found significant differences in the frequencies of the HFE genetic variants between MDS and MM patients with strong correlation to their iron metabolism. | 17001480 | 2006 | ||||
|
0.380 | GeneticVariation | group | BEFREE | The HFE gene mutations are not more frequent in MDS patients. | 27077775 | 2016 | ||||
|
0.380 | GeneticVariation | group | BEFREE | We found expected distribution of mutant HFE alleles in patients with other forms of MDS (9.1 vs. 9.8%, P = 0.82). | 17654685 | 2007 | ||||
|
0.380 | GeneticVariation | group | BEFREE | Hemochromatosis is associated with increased risk of hematological neoplasias, but studies showing hemochromatosis gene mutations in myelodysplastic syndrome (MDS) are scanty, particularly in the elderly. | 23160508 | 2012 | ||||
|
0.380 | GeneticVariation | group | BEFREE | Copper, iron and ceruloplasmin levels were established, and transferrin saturation determination and HFE mutation analysis were performed in 32 MDS patients. | 16462140 | 2006 | ||||
|
0.380 | GeneticVariation | group | BEFREE | 95.7% of patients with MDS with the presence of HFE gene variations had received more of 20 transfusions. | 25841232 | 2015 | ||||
|
0.380 | GeneticVariation | group | BEFREE | We found significant differences in the frequencies of the HFE genetic variants between MDS and MM patients with strong correlation to their iron metabolism. | 17001480 | 2006 | ||||
|
0.380 | GeneticVariation | group | BEFREE | Similarly, there was no significant difference between HFE mutant and HFE wild-type MDS and AA patients in clinical indices such as alanine aminotransferase, aspartate aminotransferase, fasting blood sugar values, and electrocardiogram. | 20563578 | 2010 | ||||
|
0.380 | Biomarker | group | BEFREE | The difference between the HFE-positive and HFE-negative MDS patients as regards initial serum iron and transferrin saturation was not significant. | 12624489 | 2003 |